LD50

median lethal dose

The average amount of a drug, toxin, chemical substance/mixture or microorganism capable of killing 1/2 of the test animals exposed under specific test conditions. Median lethal dose (LD50) is commonly expressed in mg/kg, by oral intake or skin exposure.

LD₅₀

Lethal dose₅₀, median lethal dose The radiation dose that is lethal to 50% of those exposed–2.5-6.0 Gy, assuming that optimal care—ie transfusions, trauma and nursing care, antibiotics and nutrition—is available

LD₅₀

In pharmacology, a dose that proves lethal to 50% of a given population.

LD50

The dose of a poison that kills half the subjects exposed to it. Used as a measure of the toxicity of drugs and other substances.

LD₅₀

see LETHAL DOSE.

LD₅₀

Dosage of drug or numbers of microorganisms or other pathogens that kills 50% of a test population.

Acronym

Definition

LD50➣Lethal Dose 50 (median concentration of a toxicant that will kill 50% of the test animals within a designated period)