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单词 l-dopa
释义

L-dopa


L-do·pa

L0083300 (ĕl-dō′pə)n. An isomer of dopa that is converted in the brain to dopamine and is used in synthetic form to treat Parkinson's disease. Also called levodopa.

L-dopa

(ɛlˈdəʊpə) n (Biochemistry) a substance occurring naturally in the body and used to treat Parkinson's disease. Formula: C9H11NO4. Also called: levodopa [C20: from L-d(ihydr)o(xy)p(henyl)a(lanine)]

L-do•pa

(ˌɛlˈdoʊ pə)

n. the levorotatory isomer of dopa, converted in the brain to dopamine: used in synthetic form chiefly for treating parkinsonism. Also called levodopa. [1935–40]
Thesaurus
Noun1.L-dopa - the levorotatory form of dopa (trade names Bendopa and Brocadopa and Larodopa); as a drug it is used to treat Parkinson's diseaseBendopa, Brocadopa, Larodopa, levodopadihydroxyphenylalanine, dopa - amino acid that is formed in the liver and converted into dopamine in the brain

l-dopa


l-dopa

(ĕl-dō`pə), drug used to alleviate some of the symptoms of Parkinson's diseaseParkinson's disease
or Parkinsonism,
degenerative brain disorder first described by the English surgeon James Parkinson in 1817. When there is no known cause, the disease usually appears after age 40 and is referred to as Parkinson's disease; a number of genes have
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, particularly trembling, rigidity, and slow movements; the drug is also called levodopa. Parkinson's disease results when the concentration of dopamine in the brain is depleted (see catecholaminecatecholamine
, any of several compounds occurring naturally in the body that serve as hormones or as neurotransmitters in the sympathetic nervous system. The catecholamines include such compounds as epinephrine, or adrenaline, norepinephrine, and dopamine.
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). Medical administration of dopamine itself is ineffective since that chemical apparently does not enter the brain from the blood. A metabolic precursor of dopamine, l-dopa does enter the brain via the bloodstream and is probably converted into dopamine there. Because there are many brain disorders with similar symptoms, many patients do not show any improvement when treated with the drug. Furthermore, virtually all patients on l-dopa experience side effects including nausea, loss of appetite, cardiac irregularities, and psychological changes.

L-dopa

[¦el ′dō·pə] (pharmacology) levodopa

l-dopa


dopa

 [do´pah] a compound produced by oxidation of tyrosine by tyrosinase; it is the precursor of dopamine" >dopamine and an intermediate product in the biosynthesis of norepinephrine, epinephrine, and melanin. The naturally occurring form is l-dopa" >l-dopa (see levodopa), and is used to treat parkinson's disease and other forms of parkinsonism.

le·vo·do·pa

(lē'vō-dō'pă), The biologically active form of dopa; an antiparkinsonian agent that is converted to dopamine. Synonym(s): l-dopa

L-dopa

(ĕl-dō′pə)n. An isomer of dopa that is converted in the brain to dopamine and is used in synthetic form to treat Parkinson's disease. Also called levodopa.

l-dopa

Abbreviation for levodopa.

Levodopa (L-dopa)

A substance used in the treatment of Parkinson's disease. Levodopa can cross the blood-brain barrier that protects the brain. Once in the brain, it is converted to dopamine and thus can replace the dopamine lost in Parkinson's disease.Mentioned in: Movement Disorders

L-dopa


Related to L-dopa: levodopa, dopamine, Mucuna pruriens
  • noun

Synonyms for L-dopa

noun the levorotatory form of dopa (trade names Bendopa and Brocadopa and Larodopa)

Synonyms

  • Bendopa
  • Brocadopa
  • Larodopa
  • levodopa

Related Words

  • dihydroxyphenylalanine
  • dopa
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更新时间:2024/11/12 13:32:48