单词 | adozelesin |
释义 | adozelesinadozelesinAn experimental drug belonging to the cyclopropylpyrroloindole family, which induces single-stranded DNA lesions. At low concentrations, it induces a transient S-phase block and cell-cycle arrest in G2-M, and increases induction of p53 and p21, whereas at high concentrations it only causes apoptosis. |
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