Nissl Body

(also called tigroid body), a condensed portion of the cytoplasm of a nerve cell. Nissl bodies were first described at the end of the 19th century by the German scientist F. Nissl.

Nissl bodies can be viewed under a light microscope after staining with methylene blue or other basic stains. They appear as rounded masses that occupy the entire body of the cell as well as the bases of the outgrowths. Electron microscopy reveals that the Nissl bodies contain aggregates of ribosomes and cisternae of the endoplasmic reticulum. Nissl substance, which forms the Nissl bodies, consists of ribonucleic acid (RNA), proteins, acid polysaccharides, and lipids; it participates actively in the synthesis of cell proteins.

Changes in the chemical composition, shape, and staining characteristics of Nissl bodies occur as a result of trauma to the nervous system, inflammatory or infectious diseases, poisoning, oxygen deprivation, or shifts in the function of the neurons.

REFERENCE

Peters, A., S. Palay, and H. Webster. Ul’trastruktura nervnoi sistemy. Moscow, 1972. (Translated from English.)

Nissl body

Large granular bodies found in nerve cells. They can be demonstrated by selective staining. They are rough endoplasmic reticulum (with ribosomes) and are the site of protein synthesis. Nissl bodies show changes under various physiological conditions, and in pathological conditions they may dissolve and disappear (chromatolysis). Synonym: Nissl granule See: tigroid bodies.See also: Nissl, Franz

单词	nissl body
释义	DictionarySeebody Nissl Body Nissl Body (also called tigroid body), a condensed portion of the cytoplasm of a nerve cell. Nissl bodies were first described at the end of the 19th century by the German scientist F. Nissl. Nissl bodies can be viewed under a light microscope after staining with methylene blue or other basic stains. They appear as rounded masses that occupy the entire body of the cell as well as the bases of the outgrowths. Electron microscopy reveals that the Nissl bodies contain aggregates of ribosomes and cisternae of the endoplasmic reticulum. Nissl substance, which forms the Nissl bodies, consists of ribonucleic acid (RNA), proteins, acid polysaccharides, and lipids; it participates actively in the synthesis of cell proteins. Changes in the chemical composition, shape, and staining characteristics of Nissl bodies occur as a result of trauma to the nervous system, inflammatory or infectious diseases, poisoning, oxygen deprivation, or shifts in the function of the neurons. REFERENCE Peters, A., S. Palay, and H. Webster. Ul’trastruktura nervnoi sistemy. Moscow, 1972. (Translated from English.) Nissl body Nissl body Large granular bodies found in nerve cells. They can be demonstrated by selective staining. They are rough endoplasmic reticulum (with ribosomes) and are the site of protein synthesis. Nissl bodies show changes under various physiological conditions, and in pathological conditions they may dissolve and disappear (chromatolysis). Synonym: Nissl granule See: tigroid bodies.See also: Nissl, Franz FinancialSeeBody
随便看	international organic inspectors association international organic wine expo international organisation international organisation development south africa international organisation for cooperation in evaluation international organisation for standardisation international organisation for standardization international organisation of employers international organisation of good templars international organisation of iranian refugees international organisation of overhead catenary engineers international organisation of palaeobotany international organisation of professional drivers institute for women's health institute for women's policy research institute for wood research institute for work and employment research institute for workforce development and economic sustainability institute for work & health institute for world evangelisation institute for young musicians institute growth and development institute & guild of brewing institut en génie de l’énergie électrique institute of accounting technicians