| 释义 |
LE
LE abbreviation for (Medicine) lupus erythematosus Thesaurus| Noun | 1.LE - a chronic inflammatory collagen disease affecting connective tissue (skin or joints)lupus erythematosusautoimmune disease, autoimmune disorder - any of a large group of diseases characterized by abnormal functioning of the immune system that causes your immune system to produce antibodies against your own tissueslupus - any of several forms of ulcerative skin disease |
IdiomsSeeaprès moi le delugeLeenUK
Le. For names beginning thus and not listed here, see second element; e.g., for Le Havre, see Havre, LeHavre, Le
, city (1990 pop. 195,932), Seine-Maritime dept., N France, in Normandy, at the mouth of the Seine River on the English Channel. It was founded in 1517 as Le Havre-de-Grâce by Francis I. Le Havre became a major seaport in the 19th cent.
..... Click the link for more information. .LE(1) (Less than or Equal to) See relational operator.
(2) (Local Exchange) See central office.
(3) (Little Endian) See byte order.
(2) (Low Energy) See Bluetooth LE.LE
lupus [loo´pus] a name originally given to a destructive type of skin lesion, implying a local degeneration rather than systemic involvement. Although the term is frequently used alone to designate lupus vulgaris and sometimes lupus erythematosus, without a modifier it has no meaning. The Latin word lupus means wolf; erythematosus refers to redness. The name lupus erythematosus has been used since the 13th century because physicians thought the shape and color of the skin lesions resembled the bite of a wolf. Currently, there are at least two recognized manifestations of the disease: discoid lupus erythematosus and systemic lupus erythematosus.chilblain lupus erythematosus a form of discoid lupus erythematosus aggravated by cold, initially resembling chilblains, in which the lesions consist of reddened infiltrated patches on the exposed areas of the body, especially the finger knuckles.cutaneous lupus erythematosus one of the two main types of lupus erythematosus; it may involve only the skin or may precede involvement of other body systems. It may be chronic (discoid lupus erythematosus); subacute (systemic lupus erythematosus); or acute (characterized by an acute edematous, erythematous eruption, often with systemic exacerbations). The acute form may be the presenting symptom of systemic lupus erythematosus, such as after sun exposure.discoid lupus erythematosus (DLE) a superficial inflammation of the skin, marked by red macules up to 3 to 4 cm in width, and covered with scanty adherent scales, which extend into spreading follicles that fall off and leave scars. The lesions typically form a butterfly pattern over the bridge of the nose and cheeks, but other areas may be involved, notably the scalp and other areas that are exposed to light.drug-induced lupus a syndrome closely resembling systemic lupus erythematosus, precipitated by prolonged use of certain drugs, most commonly hydralazine, isoniazid, various anticonvulsants, and procainamide.lupus erythemato´sus (LE) a group of connective tissue disorders primarily affecting women aged 20 to 40, comprising a spectrum of clinical forms in which cutaneous disease may occur with or without systemic involvement.lupus per´nio 1. soft, purplish skin lesions on the cheeks, forehead, nose, ears, and digits, frequently associated with bone cysts, which may be the first manifestation of sarcoidosis or occur in the chronic stage of the disease.2. chilblain lupus erythematosus.systemic lupus erythematosus (SLE) a chronic inflammatory disease, usually febrile and characterized by injury to the skin, joints, kidneys, nervous system, and mucous membranes. It can, however, affect any organ of the body and usually has periods of remissions and exacerbations. (See plate in Dermatology Atlas.)
It was once thought that this was a fairly rare disease, but improved immunologic testing procedures have shown that it is not. It is primarily a disease of women, occurring five to ten times more often in females than in males. Although the peak incidence is between 30 and 40 years of age, the condition has also been diagnosed in the very young and the very old.
SLE is the classic prototype of autoimmune disease of connective tissue. Its etiology is unknown, but the high level of autoantibodies in persons with the condition indicates a defect in the regulatory mechanisms that sustain self-tolerance and prevent the body from attacking its own cells, cell constituents, and proteins. Patients with SLE can have a wide variety of autoantibodies against nuclear and cytoplasmic cellular components. The presence of high levels of antinuclear antibody (ANA) in SLE patients with glomerulonephritis indicates a pathogenic role for that antibody. The antibodies are directed against deoxyribonucleoprotein, DNA, histone, and a soluble non–nucleic acid molecule called Sm antigen.
Factors that appear to contribute to the development of SLE include exposure to sunlight or ultraviolet radiation from sunlamps, a genetic predisposition to the disease, certain drugs, viral infections, and hormonal influences.
Clinical manifestations of SLE are confusingly diverse owing to the involvement of connective tissue throughout the body. Typically, the patient seeks medical help for relief of fever, weight loss, joint pain, the characteristic butterfly rash, pleural effusion and pleuritic pain, and nephritis. The detection of ANA by microscopic immunofluorescence is supportive evidence for the presence of SLE.
Either glomerulonephritis, which is usually mild, or cardiovascular manifestations such as myocarditis, endocarditis, or pericarditis, are found in about half the patients with SLE. Pulmonary disease, especially pleurisy, is also relatively common, as are gastrointestinal disturbances and lymph node involvement. Organic neurologic disturbances produce behavioral aberrations and frank psychosis in some patients; in a few others, there are peripheral neuropathies, motor weakness, and diplopia.
Supportive measures are used to prevent or minimize acute relapses and exacerbations of symptoms. The patient is instructed to avoid exposure to sunlight and ultraviolet radiation from other sources, blood transfusions, penicillin, and the sulfonamides. Active disease is treated with topical steroids, nonsteroidal antiinflammatory drugs for fever and joint pain, corticosteroids, and immunosuppressants. The goal of drug therapy is suppression of the immune system. Treatment of specific manifestations of SLE is aimed at prevention of complications. Physical therapy may be required to alleviate muscle weakness and prevent orthopedic deformities.lupus vulga´ris the most common and severe form of tuberculosis of the skin, most often affecting the face, with formation of reddish brown patches of nodules in the corium, which progressively spread peripherally with central atrophy, causing ulceration and scarring and destruction of cartilage in involved sites.LE , L.E.Abbreviation for left eye; lupus erythematosus.FUT3 A gene on chromosome 19q13.3 that encodes a fucosyltransferase with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities, which catalyses the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis.
Molecular pathology
FUT3 mutations are responsible for most Lewis antigen-negative blood group phenotypes.LE 1. Lateral epicondyle.2. Left extremity.3. Left eye.4. Leukocyte esterase
.5. Lupus erythematosus. See Systemic lupus erythematosus.LE Abbreviation for lupus erythematosus. LE Abbreviation for lupus erythematosus. Patient discussion about LEQ. Is a rash a symptom of lupus? My Sister has lupus for several years now. I recently developed a rash on my face. Is this a symptom of lupus? Could I have also been infected with this disease?A. Lupus has not been proven to be hereditary. Therefore, the fact your sister has lupus shouldn't cause you to beleive you too will develop it. Also a rash is not enough to diagnose lupus. Physicians have to gather information from a variety of sources: past medical history, lab tests and current symptoms. They use a list of 11 criteria to help diagnose SLE. A person needs to satisfy at least 4 out of the 11 criteria before the diagnosis can be pinpointed. Some criteria, such as a biopsy diagnosis of kidney lupus, can carry more weight. More discussions about LEFinancialSeeLALE
| Acronym | Definition |
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| LE➣Limited Edition | | LE➣Lebanon | | LE➣Lower East | | LE➣Lecce (italy) | | LE➣Law Enforcement | | LE➣Link Exchange | | LE➣Low Energy | | LE➣Lake Erie (Great Lakes) | | LE➣Limit(s) of Error | | LE➣Less than or Equal to (computer math) | | LE➣Life Expectancy | | LE➣Leading Edge | | LE➣Leicester (postcode, United Kingdom) | | LE➣Legal Entity | | LE➣Egyptian Pound | | LE➣Lab Equipment | | LE➣Life Extension | | LE➣Left End | | LE➣Line Equipment | | LE➣Last Exile (anime) | | LE➣Light Equipment | | LE➣Lead Engineer | | LE➣Less or Equal | | LE➣Licensed Esthetician | | LE➣Lupus Erythematosus | | LE➣Large Enterprise | | LE➣Living Education | | LE➣Lower Extremity | | LE➣Local Exchange | | LE➣Life Estate (inheritance) | | LE➣Lubrication Engineers (Fort Worth, TX) | | LE➣Lean Enterprise (management model) | | LE➣Light Entertainment | | LE➣Learning Express (toy store) | | LE➣Later Edit | | LE➣Late Entry | | LE➣Sierra Leone Leone (national currency) | | LE➣Language Environment | | LE➣Line Engraved (philately; Victorian-era style stamps) | | LE➣Leucine-Enkephalin (opioid peptide neurotransmitter) | | LE➣Lateral Epicondylitis | | LE➣Licensed Embalmer | | LE➣Left Engine | | LE➣Latest Estimate | | LE➣Leukocyte Esterase | | LE➣Large Exposure (banking) | | LE➣Ladder Edition (gaming) | | LE➣Low Efficiency | | LE➣Luxury Edition | | LE➣LAN Emulation | | LE➣Legendary Event ((Fallensword gaming) | | LE➣Lead Equivalent | | LE➣Laplacian Eigenmap (algorithm) | | LE➣Lactation Educator | | LE➣Laser Engineer | | LE➣Liquid-Expanded (physics) | | LE➣Language Extender (Microsoft Windows CE) | | LE➣Launch Escape | | LE➣Lyapunov Exponent | | LE➣Linear Error | | LE➣Lawful Evil (gaming) | | LE➣Logic Element | | LE➣Laptop Environment | | LE➣Low Explosive | | LE➣Link Enable(d) | | LE➣Loteprednol Etabonate | | LE➣Louisiana Eastern (railroad) | | LE➣Link Encapsulation (ATM) | | LE➣Locus Equations | | LE➣Long Eireannach (Gaelic: Ship of Ireland) | | LE➣Lil’ Ethan (character in NBC's Passions) | | LE➣Ludus Equinus (gaming website) | | LE➣Limited Egress | | LE➣Listener Echo-Loss |
LE
Synonyms for LEnoun a chronic inflammatory collagen disease affecting connective tissue (skin or joints)SynonymsRelated Words- autoimmune disease
- autoimmune disorder
- lupus
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