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Okazaki fragment
Okazaki fragment[‚ō·kə¦zä·kē ‚frag·mənt] (cell and molecular biology) In deoxyribonucleic acid replication, a discontinuous segment in which the lagging strand is synthesized. Okazaki fragment
O·ka·za·ki frag·ment (ō-kă-ză'kē), a relatively short (100-2000 bp in Escherichia coli and 100-200 bp in mammals) fragment of DNA that is later joined by DNA ligase to allow for 3' → 5' overall chain growth during replication. [Reiji Okazaki] Okazaki fragment see DNA (b) REPLICATION.Okazaki, Reiji, Japanese biochemist, 1930-1975. Okazaki fragment - short pieces of DNA formed during DNA synthesis. |