systemic anaphylaxis


gen·er·al·ized an·a·phy·lax·is

(jen'ĕr-ă-līzd an'ă-fi-lak'sis) The immediate response, involving smooth muscles and capillaries throughout the body, which follows injection of antigen (allergen).
See also: anaphylactic shock
Synonym(s): systemic anaphylaxis.

systemic anaphylaxis

A reaction between IgE antibodies bound to mast cells and an allergen that causes the sudden release of immunological mediators in the skin, respiratory, cardiovascular, and gastrointestinal systems. The consequences may range from mild, e.g., itching, hives, to life-threatening (airway obstruction and shock). See also: anaphylaxis