| 释义 |
systemic capillary leak syndrome systemic capillary leak syndromea rare disorder of unknown cause presenting with episodic hypotension, hemoconcentration, and hypoalbuminemia; monoclonal gammopathy is often associated.
systemic capillary leak syndromea rare disorder of unknown cause presenting with episodic hypotension, hemoconcentration, and hypoalbuminemia; monoclonal gammopathy is often associated.A condition in which the size of the pores in the capillaries are increased, leading to a leakage of 10+ litres of fluid into the interstitial space, resulting in haemoconcentration, hypoalbuminaemia, severe hypotension, generalised oedema and multiple organ failure— cardiopulmonary collapse, and acute renal failure—due to acute tubular necrosis following hypovolemia, rhabdomyolysis, due to reduced perfusion, causing progressive dyspnea and pericarditis, high fever, confusion, and disorientation
Aetiology Cytokine therapy with IL-2, GM-CSF, used to treat metastatic cancer
Prognosis The high mortality in early reports has been reduced by prophylactic therapy using terbutaline, theophyllinsys·tem·ic cap·il·lar·y leak syn·drome (sis-tem'ik kap'i-lar-ē lēk sin'drōm) A rare disorder of unknown cause presenting with episodic hypotension, hemoconcentration, and hypoalbuminemia; monoclonal gammopathy is often associated. systemic capillary leak syndromeA rare disease whose hallmarks are episodes of hypotension associated with extravasation of plasma from the systemic circulation. |