systemic mast cell disease

a heterogeneous group of diseases with four major divisions: indolent mastocystosis, the most common, which involves skin (for example, urticaria pigmentosa), marrow, and the gastrointestinal tract; mastocytosis with an associated hematologic disorder (that is, mast cell infiltrates in marrow, spleen, liver, and lymph nodes); mast cell leukemia (that is, immature mast cells infiltrating marrow, peripheral blood, and extramedullary tissues); and aggressive mastocytosis (that is, accumulation of mast cells in various organs, release of mast cell mediators producing a clinical sign).

单词	systemic mast cell disease
释义	systemic mast cell disease systemic mast cell disease a heterogeneous group of diseases with four major divisions: indolent mastocystosis, the most common, which involves skin (for example, urticaria pigmentosa), marrow, and the gastrointestinal tract; mastocytosis with an associated hematologic disorder (that is, mast cell infiltrates in marrow, spleen, liver, and lymph nodes); mast cell leukemia (that is, immature mast cells infiltrating marrow, peripheral blood, and extramedullary tissues); and aggressive mastocytosis (that is, accumulation of mast cells in various organs, release of mast cell mediators producing a clinical sign).
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