oxidatively modified low density lipoprotein

A form of low-density lipoprotein that is modified in vivo and thought to play a key role in the development of atherosclerosis, given that its uptake by macrophages and smooth muscle cells leads to formation of foam cells, a critical step in atherosclerosis. Circulating OxLDL concentrations reflect the state of pathological atherosclerosis and are biochemical risk marker for coronary artery disease (CAD). OxLDL can be quantified by measuring malondialdehyde-modified LDL, which more accurately reflect CAD than surrogate markers such as cholesterol, HDL and LDL

单词	oxidatively modified low density lipoprotein
释义	oxidatively modified low density lipoprotein oxidatively modified low density lipoprotein A form of low-density lipoprotein that is modified in vivo and thought to play a key role in the development of atherosclerosis, given that its uptake by macrophages and smooth muscle cells leads to formation of foam cells, a critical step in atherosclerosis. Circulating OxLDL concentrations reflect the state of pathological atherosclerosis and are biochemical risk marker for coronary artery disease (CAD). OxLDL can be quantified by measuring malondialdehyde-modified LDL, which more accurately reflect CAD than surrogate markers such as cholesterol, HDL and LDL
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