| 释义 |
Warburg effect
Warburg effect The observation—first made by Otto Heinrich Warburg—that most malignant cells get their energy from anaerobic metabolism, at rates of glycolysis of up to 200-fold greater than oxidative metabolism of pyruvate in mitochondria. This effect led Warburg to assume that the fundamental change in cancer was metabolic rather than genetic. Some practitioners of alternative forms of healthcare continue to believe the Warburg effect can be exploited by reducing the energy available to malignant cells using hydrazine sulphate and other agents.Warburg effectThe reliance of most cancer cells on glycolysis rather than oxidation to meet their metabolic needs.See also: Warburg, Otto H. |