quinolones


quin·o·lones

(kwin'ō-lōnz), A class of synthetic broad-spectrum antibacterial agents with bactericidal action (for example, ciprofloxacin).

quin·o·lones

(kwin'ō-lōnz) A group of antimicrobial agents (e.g., norfloxacin, ciprofloxacin, levofloxacin) that block bacterial DNA synthesis.

quinolones

A group of synthetic antibiotic drugs that includes nalidixic acid, oxfloxacin and enoxacin. These drugs act by inactivating an enzyme, DNA gyrase, necessary for replication of the organisms.

quinolones 

A class of broad-spectrum antibacterial drugs of which the main ophthalmic agents are ciprofloxacin and ofloxacin. They are used topically in 0.3% solution. They are effective against the majority of gram-negative pathogens, including Haemophilus, Neisseria gonorrhoeae, Chlamydia trachomatis, Pseudomonas aeruginosa (especially ciprofloxacin), staphylococci and streptococci. They are used in the treatment of conjunctivitis, blepharitis, keratoconjunctivitis and corneal ulcers. See antibiotic.

quin·o·lones

(kwin'ō-lōnz) Synthetic broad-spectrum antibacterial agents with bactericidal action.