单词 | adriamycin |
释义 | adriamycinenUKadriamycin(ˌeɪdrɪəˈmaɪsɪn)AdriamycinenUKAdriamycin[a″dre-ah-mi´sin]dox·o·ru·bi·cin(doks'ō-rū'bi-sin),Adriamycin(ā′drē-ə-mī′sən)AdriamycinAn anthracycline antibiotic with antineoplastic activity, which is used to treat haematologic malignancies, especially leukaemias, but also carcinomas and solid tumours (for which it is not particularly effective); its efficacy is hampered by cardiotoxicity that increases as the cumulative dose passes 500 mg/mm3.Adverse effects Nausea, vomiting, neutropenia; about one-fourth of Adriamycin-treated patients develop late cardiac abnormalities once the cumulative dose passes 450 mg/mm2 including cardiac failure, dysrhythmia and sudden death; post-mortem examination of the heart reveals myocardial fibrosis. adriamycinDoxorubicin HCl Oncology An anthracycline antibiotic with antineoplastic activity, used to treat both leukemia and solid tumors; its efficacy is hampered by cardiotoxicity that ↑ as the cumulative dose passes 500 mg/mm3AdriamycinDoxorubicin. An anticancer drug which acts by interfering with cell division. |
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