| 释义 |
skin/hair/eye pigmentation type 2 skin/hair/eye pigmentation type 2 A genetic variation of hair, eye and skin pigmentation typical of populations living further from the equator (e.g., northern Europeans). Individuals with SHEP2 often have partial loss-of-function mutations of MC1R, which encodes melanocortin 1 receptor, and are characterised by fair skin, blonde or red hair, poor tanning and increased risk of skin cancer due to increased susceptibility to UV-light-induced skin damage. |