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secretinenUK
se·cre·tin S0206800 (sĭ-krēt′n)n. A polypeptide hormone that is produced in the duodenum, especially on contact with acid, and that inhibits gastric secretion of acid and stimulates secretion of bile, insulin, and pancreatic digestive enzymes.
[secret(ion) + -in.]secretin (sɪˈkriːtɪn) n (Physiology) a peptic hormone secreted by the mucosae of the duodenum and jejunum when food passes from the stomach[C20: from secretion + -in]se•cre•tin (sɪˈkri tɪn)
n. a polypeptide hormone, produced in the small intestine, that activates the pancreas to secrete pancreatic juice. [< German Secretin (1902); see secretion, -in1] Thesaurus| Noun | 1. | secretin - a gastrointestinal hormone that stimulates the secretion of water and bicarbonate from the pancreas and bile ducts whenever the stomach empties too much acid into the small intestinegastrointestinal hormone, GI hormones - hormones that affect gastrointestinal functioning |
TranslationsSecretinenUK
secretin[si′krēt·ən] (biochemistry) A basic polypeptide hormone produced by the duodenum in response to the presence of acid; acts to excite the pancreas to activity. Secretin a hormone substance (tissue hormone) secreted by the mucosa of the upper portion of the small intestine that participates in the regulation of pancreatic secretion. Secretin was discovered in 1902 by the British physiologists W. Bayliss and E. Starling. (Starling introduced the concept of the hormone into science in 1905 as a result of his study of secretin.) Chemically, secretin is a peptide consisting of 27 amino-acid residues, 14 of which are in the same sequence as in glucagon. Secretin is obtained in a pure form from the intestinal mucosa of swine. It is released mainly under the influence of the hydrochloric acid of gastric juice, which enters the duodenum with chyme, a gruel-like material. Secretion can be induced experimentally by introducing dilute acid into the small intestine. Secretin is absorbed by the blood and travels to the pancreas, where it intensifies the secretion of water and electrolytes, especially bicarbonate. Secretin increases the volume of pancreatic juice secreted but does not affect the production of pancreatic enzymes. The latter function is performed by pancreozymin, a substance elaborated in the intestinal mucosa. The biological determination of secretin is based on its ability to make the pancreatic juice more alkaline when injected intravenously into animals. Secretin has been synthesized chemically. REFERENCESClegg. C., and A. Clegg. Gormony, kletki, organizm, ch. 13. Moscow, 1971. (Translated from English.)
Gastrointestinal Hormones. Stuttgart, 1972.A. A. BULATOV secretinenUK
se·cre·tin (se-krē'tin), [MIM*182099] A hormone, formed by the epithelial cells of the duodenum under the stimulus of acid contents from the stomach, which incites secretion of pancreatic juice; used as a diagnostic aid in the diagnosis of pancreatic exocrine disease and as an adjunct in obtaining desquamated pancreatic cells for cytologic examination. Synonym(s): oxykrinin [secrete + -in] secretin (sĭ-krēt′n)n. A polypeptide hormone that is produced in the duodenum, especially on contact with acid, and that inhibits gastric secretion of acid and stimulates secretion of bile, insulin, and pancreatic digestive enzymes.se·cre·tin (sĕ-krē'tin) A hormone, formed by the epithelial cells of the duodenum under the stimulus of acid contents from the stomach, that incites secretion of pancreatic juice; used as an aid in the diagnosis of pancreatic exocrine disease and as an adjunct in obtaining desquamated pancreatic cells for cytologic examination.
Compare: bioregulatorsecretin A hormone secreted in the DUODENUM that prompts the production of PANCREATIC JUICE.secretin a hormone responsible for the secretion of bile from the liver.se·cre·tin (sĕ-krē'tin) [MIM*182099] Hormone formed by epithelial cells of duodenum under stimulus of acid contents from stomach, which incites secretion of pancreatic juice. AcronymsSeeSCTsecretinenUK
Related to secretin: cholecystokinin, CCK, secretin testWords related to secretinnoun a gastrointestinal hormone that stimulates the secretion of water and bicarbonate from the pancreas and bile ducts whenever the stomach empties too much acid into the small intestineRelated Words- gastrointestinal hormone
- GI hormones
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