单词 | topoisomerase 1 inhibitor drugs |
释义 | topoisomerase 1 inhibitor drugstopoisomerase 1 inhibitor drugsA range of drugs that interfere with DNA replication by inhibiting the action of the topoisomerase enzymes that allow the uncoiling of the double helix-a necessary preliminary to replication. They are used as anticancer drugs and, by local application, to treat warts. Examples are topotecan (Hycamtin) and irinotecan (Campto). |
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