a purulent inflammation of all the tissues and membranes of the eye. The chief cause is an infected wound of the eyeball; occasionally its origin is an infection brought from another inflammatory focus. The most common causative agents are Pneumococci, Staphylococci, and Streptococci. Panophthalmitis is accompanied by sharp pains in the eye, general intoxication, chills, fever, and vomiting and may result in loss of the eye. It is treated with sulfanilamide preparations and antibiotics; in severe cases the affected eyeball is removed.