| 释义 |
thromboplastin
throm·bo·plas·tin T0189500 (thrŏm′bō-plăs′tĭn)n. A complex of protein and phospholipids that is found in tissues and platelets and facilitates blood clotting by converting prothrombin to thrombin.thromboplastin (ˌθrɒmbəʊˈplæstɪn) n (Biochemistry) any of a group of substances that are liberated from damaged blood platelets and other tissues and convert prothrombin to thrombin. Also called: thrombokinase throm•bo•plas•tin (ˌθrɒm bəˈplæs tɪn)
n. a lipoprotein in the blood that converts prothrombin to thrombin. Also called throm•bo•ki•nase (ˌθrɒm boʊˈkaɪ neɪs, -ˈkɪn eɪs) [1910–15]Thesaurus| Noun | 1. | thromboplastin - an enzyme liberated from blood platelets that converts prothrombin into thrombin as blood starts to clotfactor III, thrombokinaseclotting factor, coagulation factor - any of the factors in the blood whose actions are essential for blood coagulation |
thromboplastin
thromboplastin: see blood clottingblood clotting,
process by which the blood coagulates to form solid masses, or clots. In minor injuries, small oval bodies called platelets, or thrombocytes, tend to collect and form plugs in blood vessel openings.
..... Click the link for more information. .Thromboplastin (Factor III), an important coagulation factor in the blood-clotting system; it helps convert prothrombin into thrombin. Thromboplastin is localized in the membranes of formed elements of the blood and in the cells of various organs. A large amount of thromboplastin enters the blood upon injury to tissues. Brain and lung tissues have especially high thrombo-plastic activity, and lung thromboplastin also takes part in the metabolism of the vasoactive polypeptides angiotensin and bradykinin. Chemically, thromboplastin is a protein-lipid complex. The basis of its activity is its lipid constituent, which contains serine, eth-anolamine, and choline phosphatides. Blood coagulation factors are adsorbed on the phospholipid micelle, creating favorable conditions for the enzymatic reactions involved in blood clotting. The term “thromboplastin” is sometimes used to designate an active complex that includes, in addition to thromboplastin, a number of protein factors and Ca2+ ions. Such active thromboplastin, which directly converts prothrombin into thrombin, is also called thrombokinase or prothrombinase. Thromboplastin is used in clinical practice to determine the prothrombin level, an indicator of the condition of the blood-clotting system. I. P. BASKOVA thromboplastin[‚thräm·bō′plas·tən] (biochemistry) Any of a group of lipid and protein complexes in blood that accelerate the conversion of prothrombin to thrombin. Also known as factor III; plasma thromboplastin component (PTC). thromboplastin
thromboplastin [throm″bo-plas´tin] tissue thromboplastin.tissue thromboplastin factor III, a coagulation factor derived from several different sources in the body, such as brain and lung; it is important in the formation of extrinsic prothrombin converting principle in the pathway of coagulation" >extrinsic pathway of coagulation. Called also tissue factor. See also time" >activated partial thromboplastin time.throm·bo·plas·tin (throm'bō-plas'tin), A substance present in tissues, platelets, and leukocytes necessary for the coagulation of blood; in the presence of calcium ions thromboplastin is necessary for the conversion of prothrombin to thrombin, an important step in coagulation of blood. It is now generally believed that thromboplastin activity may be developed through blood (intrinsic) or tissue (extrinsic) systems. Tissue thromboplastin (factor III) interacts with factor VII and calcium to activate factor X; active factor X combines with factor V in the presence of calcium and phospholipid to produce thromboplastin activity (also commonly called thromboplastin). Synonym(s): platelet tissue factor, thrombokinase, thrombozyme, tissue factor, zymoplastic substancethromboplastin (thrŏm′bō-plăs′tĭn)n. A protease that converts prothrombin to thrombin in the early stages of blood clotting. Also called thrombokinase.throm·bo·plas·tin (throm'bō-plas'tin) A substance present in tissues, platelets, and leukocytes necessary for the coagulation of blood; in the presence of calcium ions, thromboplastin is necessary for the conversion of prothrombin to thrombin, an important step in blood coagulation.
Synonym(s): platelet tissue factor, thrombokinase. thromboplastin Blood clotting factor III, an obsolete term referring to what is now known to be several blood clotting factors operating together.thromboplastin see BLOOD CLOTTING.ThromboplastinA protein in blood that converts prothrombin to thrombin.Mentioned in: Prothrombin Timethrom·bo·plas·tin (throm'bō-plas'tin) A substance present in tissues, platelets, and leukocytes necessary for the coagulation of blood.
Synonym(s): platelet tissue factor, thrombokinase. thromboplastin
Related to thromboplastin: Prothrombin timeSynonyms for thromboplastinnoun an enzyme liberated from blood platelets that converts prothrombin into thrombin as blood starts to clotSynonymsRelated Words- clotting factor
- coagulation factor
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