squalamine

squalamine

(skwā′lĭ-mēn″) [L. squalus, dogfish + ″] An antiangiogenic protein, originally isolated from dog sharks. It has been used to treat the neovascularization of age-related macular degeneration and to limit blood vessel proliferation needed by a cancer for it to spread and survive.

squalamine

A drug extracted from the dogfish that has been claimed to be capable of killing a range of sexually-transmitted bacteria including the gonococcus and Chlamydia and of killing cells invaded by viruses.