squamous intraepithelial neoplasia

squamous intraepithelial neoplasia

A generic term for the range of premalignant lesions of the oral squamous epithelium, which follows the widely used nomenclature of the uterine cervix. SIN 1 corresponds to the 2005 WHO classification’s mild dysplasia, SIN 2 to moderate dysplasia and SIN 3 to the WHO’s severe dysplasia and carcinoma in situ.