| 单词 | self-tolerance |
| 释义 | self-toleranceself-tol·er·ance(sĕlf′tŏl′ər-əns)self-toleranceself-tolerance[self-tol´er-ans]hor·ror au·to·tox·'i·cusself-tolerance(sĕlf′tŏl′ər-əns)self-toleranceimmunological tolerance to the body's own ANTIGENS (self antigens), achieved by preventing the production of functional B-CELLS and T-CELLS reactive to such antigens. Thus the body is not able to direct an IMMUNE RESPONSE against self antigens. Breakdown of this mechanism leads to AUTOIMMUNITY and production of autoantibodies against self antigens. |
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