| 单词 | bap1 |
| 释义 | BAP1BAP1A gene on chromosome 3p21.31-p21.2 that encodes a tumour-suppressing enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A and HCFC1. BAP1 forms the catalytic component of the PR-DUB complex, which specifically mediates deubiquitination of histone H2A monoubiquitinated at “Lys-119”. BAP1 is also a less preferred gene symbol for what is now designated as MAGI1, see there. |
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