axonotmesis


axonotmesis

 [ak″son-ot-me´sis] nerve injury characterized by disruption of the axon and myelin sheath but with preservation of the connective tissue fragments, resulting in degeneration of the axon distal to the injury site; regeneration of the axon is spontaneous and of good quality.

ax·on·ot·me·sis

(ak'son-ot-mē'sis), Interruption of the axons of a nerve that results in degeneration of its distal (peripheral) segment (wallerian degeneration) without appreciable damage to the supporting structures (endoneurium; perineurium; epineurium) of the nerve at the site of the injury.
See also: neurapraxia, neurotmesis. [axon + G. tmēsis, a cutting]

axonotmesis

Disruption and damage to axons and the myelin sheath with Wallerian degeneration, without disruption of schwann cells, the endoneurium, perineurium or epineurium, which is caused by greater and more prolonged mechanical trauma, and a longer and more profound neurosensory deficit than that seen in neuropraxia.

ax·on·ot·me·sis

(ak'son-ot-mē'sis) Interruption of the axons of a nerve followed by complete degeneration of the peripheral segment, without severance of the supporting structure of the nerve; such a lesion may result from pinching, crushing, or prolonged pressure.
See also: neurapraxia, neurotmesis[axon + G. tmēsis, a cutting]

axonotmesis

A severe injury to a peripheral nerve without severance of the sheath, so that, although the nerve fibres may have degenerated, regeneration and ultimate recovery of function is possible. Regeneration, if it occurs, does so at a rate of somewhat less than 1 mm per day.