| 单词 | vitamin b6 -dependency syndromes |
| 释义 | vitamin B6 -dependency syndromesvitamin B6 -dependency syndromesA group of functional or structural enzyme defects that respond to a megadoses–50-100-fold > minimum daily requirements of pyridoxine Examples Vitamin B6-dependent convulsions, vitamin B6-responsive anemia, xanthurenic aciduria, cystathioninuria, homocystinuria, possibly due to a defective structure of the apoenzyme, its coenzyme binding site or coenzyme synthesis Clinical Predominantly neurologic–eg, mental retardation, psychiatric Sx, seizures, convulsions, ataxia, spasticity, peripheral neuropathy |
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