triiodothyronine resin uptake test

triiodothyronine

[tri″i-o″do-thi´ro-nēn] a thyroid hormone that contains iodine" >iodine and is liberated from thyroglobulin" >thyroglobulin by hydrolysis. It has several times the biologic activity of thyroxine.free triiodothyronine the fraction of triiodothyronine in the serum that is not bound to a binding protein.triiodothyronine resin uptake test a thyroid function test, measuring how many sites on thyroxine-binding globulin (TBG) are occupied by endogenous triiodothyronine (T₃) and how many sites remain available. An excess of radioactive exogenous triiodothyronine is added to the sample, followed by the addition of a resin that also binds T₃. A portion of the radioactive T₃ binds to sites on TBG not already occupied by endogenous thyroid hormones, and the remainder binds to the resin. The amount of labeled hormones bound to the resin (the uptake" >triiodothyronine resin uptake) can be subtracted from the total that was added and the remainder is the amount that bound to the unoccupied binding sites on the thyroxine-binding globulin.

单词	triiodothyronine resin uptake test
释义	DictionarySeetriiodothyronineEncyclopediaSeeTriiodothyronine triiodothyronine resin uptake test triiodothyronine [tri″i-o″do-thi´ro-nēn] a thyroid hormone that contains iodine" >iodine and is liberated from thyroglobulin" >thyroglobulin by hydrolysis. It has several times the biologic activity of thyroxine.free triiodothyronine the fraction of triiodothyronine in the serum that is not bound to a binding protein.triiodothyronine resin uptake test a thyroid function test, measuring how many sites on thyroxine-binding globulin (TBG) are occupied by endogenous triiodothyronine (T₃) and how many sites remain available. An excess of radioactive exogenous triiodothyronine is added to the sample, followed by the addition of a resin that also binds T₃. A portion of the radioactive T₃ binds to sites on TBG not already occupied by endogenous thyroid hormones, and the remainder binds to the resin. The amount of labeled hormones bound to the resin (the uptake" >triiodothyronine resin uptake) can be subtracted from the total that was added and the remainder is the amount that bound to the unoccupied binding sites on the thyroxine-binding globulin.
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