释义 |
DictionarySeepkprekallikrein
prekallikrein [pre-kal″ĭ-kre´in] a plasma protein that is the proenzyme of plasma kallikrein; it is cleaved to its active enzyme form by activated coagulation factor XII.pre·kal·li·kre·in (prē'kal-ĭ-krē'in), A plasma glycoprotein that in complex with kininogen serves as a cofactor in the activation of factor XII. Prekallikrein also serves as the proenzyme for plasma kallikrein. Synonym(s): Fletcher factorpre·kal·li·kre·in (prē'kal-i-krē'in) A plasma glycoprotein that in complex with kininogen serves as a cofactor in the activation of factor XII; also serves as the proenzyme for plasma kallikrein. Synonym(s): Fletcher factor. Fletcher, surname of the patient in whom the defect was first noted. Fletcher defect - slow contact activation in coagulation of the blood.Fletcher factor - factor found in coagulation studies, revealing a slow contact activation but not associated with bleeding abnormalities. Synonym(s): prekallikreinpre·kal·li·kre·in (prē'kal-i-krē'in) A plasma glycoprotein that in complex with kininogen serves as a cofactor in the activation of factor XII; also serves as the proenzyme for plasma kallikrein. Synonym(s): Fletcher factor. FinancialSeePKThesaurusSeeFletcher |