| 释义 |
variola major
Thesaurus| Noun | 1. |  variola major - a highly contagious viral disease characterized by fever and weakness and skin eruption with pustules that form scabs that slough off leaving scarssmallpox, variolapox - a contagious disease characterized by purulent skin eruptions that may leave pock marksalastrim, Cuban itch, Kaffir pox, milk pox, pseudosmallpox, pseudovariola, variola minor, West Indian smallpox, white pox - a mild form of smallpox caused by a less virulent form of the viruspock - a pustule in an eruptive disease | | 2. | variola major - a type of smallpox virus that has a fatality rate of up to 25 percentvariola major virussmallpox virus, variola virus - the virus that causes smallpox in humans; can be used as a bioweapon |
EncyclopediaSeesmallpoxvariola major
small·pox (smawl'poks), An acute eruptive contagious disease caused by a poxvirus (Orthopoxvirus, a member of the family Poxviridae) and marked at the onset by chills, high fever, backache, and headache. In 2-5 days these constitutional symptoms subside and an eruption appears as papules, which become umbilicated vesicles, develop into pustules, dry, and form scabs that, on falling off, leave a permanent marking of the skin (pock marks). The average incubation period is 8-14 days. As a result of increasingly aggressive vaccination programs carried out over a period of about 200 years, smallpox is now extinct. Synonym(s): variola major, variola [E. small pocks, or pustules] Smallpox was a universally dreaded scourge for more than 3 millennia, with case fatality rates sometimes exceeding 20%. In many ways a unique disease, it had no nonhuman reservoir species and no asymptomatic human carriers. First subjected to some control by variolation in the 10th century in India and China, it was gradually suppressed in the industrialized world after Edward Jenners 1776 landmark demonstration that infection with the harmless cowpox (vaccinia) virus renders humans immune to the smallpox virus. The last case diagnosed in the U.S. occurred in 1949. A global eradication program was initiated by the World Health Organization in 1966, and the last naturally occurring case of the disease was reported in Somalia in 1977. Routine vaccination against smallpox, discontinued in the 1970s, has been resumed for military and health care personnel and others who would be at high risk if smallpox virus should be used as a weapon of biologic warfare or bioterrorism. va·ri·o·la ma·jor (var-ī'ō-lă mā'jŏr) Severe form of smallpox. variola majorSmallpox with its full-blown, classic symptoms. Synonym: variola veraSee also: variolavariola major
Related to variola major: variola minor, Variola veraSynonyms for variola majornoun a highly contagious viral disease characterized by fever and weakness and skin eruption with pustules that form scabs that slough off leaving scarsSynonymsRelated Words- pox
- alastrim
- Cuban itch
- Kaffir pox
- milk pox
- pseudosmallpox
- pseudovariola
- variola minor
- West Indian smallpox
- white pox
- pock
noun a type of smallpox virus that has a fatality rate of up to 25 percentSynonymsRelated Words- smallpox virus
- variola virus
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