| Acronym | Definition | 
|---|
| RPLS➣Reversible Posterior Leukoencephalopathy Syndrome | 
| RPLS➣Rolling Prairie Library System (Decatur, IN) | 
| RPLS➣Registered Professional Land Surveyor | 
| RPLS➣Real Property Law Section (various locations) | 
| RPLS➣Retrofit Pulse Lubrication System (Wartsila) | 
| RPLS➣Ramus Posterolateralis Sinister (Latin; biology) | 
| RPLS➣Roughness Penalized Least Squares | 
| RPLS➣Restructuring, Planning and Leave Share (US IRS) |