thyrotropin alfa


thyrotropin

 [thi´ro-tro″pin, thi-rot´rah-pin] a hormone secreted by the anterior lobe of the pituitary gland" >pituitary gland that has an affinity for and specifically stimulates the thyroid gland. Called also thyroid-stimulating hormone.thyrotropin alfa a recombinant form of human thyrotropin; it binds to thyrotropin receptors and stimulates the steps in thyroid hormone synthesis, including iodine uptake and synthesis and secretion of thyroglobulin; used as a diagnostic adjunct in serum thyroglobulin testing, with or without radioiodine scanning, in followup of patients with well-differentiated thyroid cancer, administered intramuscularly.thyrotropin-releasing hormone stimulation test (thyrotropin-releasing hormone test) a thyroid function test that assesses release of thyrotropin by the pituitary gland; a bolus of hormone" >thyrotropin-releasing hormone is administered and serum concentrations of thyrotropin are assessed at intervals; if serum levels do not increase within 30 to 40 minutes, the pituitary thyrotrophs are dysfunctional. Called also TRH test and TRH stimulation test.