arteriosclerosis

ar·te·ri·o·scle·ro·sis

A0442400 (är-tîr′ē-ō-sklə-rō′sĭs)n. Any of several chronic diseases, such as atherosclerosis, that are characterized by thickening and loss of elasticity of the walls of the arteries and that lead to impaired blood circulation.

ar·te′ri·o·scle·rot′ic (-rŏt′ĭk) adj.

arteriosclerosis

(ɑːˌtɪərɪəʊsklɪəˈrəʊsɪs) n, pl -ses (-siːz) (Pathology) a pathological condition of the circulatory system characterized by thickening and loss of elasticity of the arterial walls. Nontechnical name: hardening of the arteries arteriosclerotic adj

ar•te•ri•o•scle•ro•sis

(ɑrˌtɪər i oʊ skləˈroʊ sɪs)

n. abnormal thickening and loss of elasticity in the arterial walls. [1885–90] ar•te`ri•o•scle•rot′ic (-ˈrɒt ɪk) adj.

ar·te·ri·o·scle·ro·sis

(är-tîr′ē-ō-sklə-rō′sĭs) A thickening and hardening of the walls of the arteries that interferes with the circulation of the blood. It can be caused by disease and is also associated with high blood pressure and diets that are rich in cholesterol and saturated fats. See also atherosclerosis.

Thesaurus

Noun

arteriosclerosis - sclerosis of the arterial walls arterial sclerosis, coronary-artery disease, hardening of the arteries, induration of the arteriesatherosclerosis, coronary artery disease - a stage of arteriosclerosis involving fatty deposits (atheromas) inside the arterial walls, thus narrowing the arteriesarteriosclerosis obliterans - a stage of arteriosclerosis involving closure of blood vesselsinduration, sclerosis - any pathological hardening or thickening of tissue

Translations

artériosclérosearteriosclerosi

arteriosclerosis

(ärtĭr'ēōsklərō`sis), general term for a condition characterized by thickening, hardening, and loss of elasticity of the walls of the blood vessels. These changes are frequently accompanied by accumulations inside the vessel walls of lipids, e.g., cholesterol; this condition is frequently referred to as atherosclerosis. Initially lesions are formed on the arterial walls, which results in blistering and the accumulation of low-density cholesterol. This produces higher blood pressure, which facilitates the imbedding of cholesterol and calcium in the vessel walls. The fatty material accumulates calcium and produces hard plaques, thus hardening the walls of the vessels. As the vessel walls thicken, the passageways through the vessels narrow, decreasing the blood supply to the affected region. Constriction of the coronary arteries may affect the heart (see coronary artery diseasecoronary artery disease,
condition that results when the coronary arteries are narrowed or occluded, most commonly by atherosclerotic deposits of fibrous and fatty tissue. Coronary artery disease is the most common underlying cause of cardiovascular disability and death.
..... Click the link for more information. , heart diseaseheart disease,
any of several abnormalities of the heart and its function in maintaining blood circulation. Heart disease is the cause of approximately half the deaths in the United States each year.
..... Click the link for more information. ). If the leg vessels are affected, there may be pain with walking and an onset of gangrene. When there is total clotting of a vessel (thrombosisthrombosis
, obstruction of an artery or vein by a blood clot (thrombus). Arterial thrombosis is generally more serious because the supply of oxygen and nutrition to an area of the body is halted.
..... Click the link for more information. ) the result may be a heart attack (if it occurs in the coronary arteries) or strokestroke,
destruction of brain tissue as a result of intracerebral hemorrhage or infarction caused by thrombosis (clotting) or embolus (obstruction in a blood vessel caused by clotted blood or other foreign matter circulating in the bloodstream); formerly called apoplexy.
..... Click the link for more information. (if in cerebral arteries).

Arteriosclerosis risk factors include hypertensionhypertension
or high blood pressure,
elevated blood pressure resulting from an increase in the amount of blood pumped by the heart or from increased resistance to the flow of blood through the small arterial blood vessels (arterioles).
..... Click the link for more information. , elevated levels of fats in the blood, cigarette smoking, diabetes mellitus, and obesity. Genetic risks are related to the ability of the body to process (uptake and metabolize) low-density lipids that contain cholesterol. Reduction of body cholesterol to normal levels through cholesterol-lowering drugs and a restricted-fat diet is usually prescribed. The latter generally entails substitution of vegetable fats for animal fats, although the use of trans fats, artificially hydrogenated vegetable oils found in margarine and vegetable shortening, was linked to increased risk of coronary disease, and they have been banned or restricted in packaged foods in the United States and other nations. Treatment of hypertension, stress management, and cessation of smoking are also important. Increasing consumption of antioxidants and folic acid may be protective. Surgical treatment that bypasses clogged areas or procedures such as angioplastyangioplasty
, any surgical repair of a blood vessel, especially balloon angioplasty or percutaneous transluminal coronary angioplasty, a treatment of coronary artery disease.
..... Click the link for more information. are sometimes necessary; gene therapy that forces the growth of new blood vessels bypassing an area has also been used. Exercise often can increase utilization of excess low-density lipids. Although the relationship between blood cholesterol levels and arteriosclerosis is not fully understood, the utilization of low-density lipids appears to be a primary indicator of the risk of arteriosclerosis.

arteriosclerosis

[är‚tir·ē·ō·sklə′rō·səs] (medicine) A degenerative arterial disease marked by hardening and thickening of the vessel walls.

arteriosclerosis

a pathological condition of the circulatory system characterized by thickening and loss of elasticity of the arterial walls

arteriosclerosis

[ahr-te″re-o-sklĕ-ro´sis] any of a group of diseases characterized by thickening and loss of elasticity of the arterial walls; popularly called “hardening of the arteries.” Symptoms depend on the organ system involved. adj., adj arteriosclerot´ic.
There are three main forms of arteriosclerosis: (1) atherosclerosis, the most common type, in which plaques of fatty deposits form in the inner layer (tunica intima) of the arteries; (2) Mönckeberg's arteriosclerosis, called also medial calcific sclerosis because of involvement of the middle layer (tunica media) of the arteries, where there is destruction of muscle and elastic fibers and formation of calcium deposits; and (3) arteriolar sclerosis or arteriolosclerosis, which is marked by thickening of the walls of arterioles. All three forms may be present in the same patient, but in different blood vessels. When reference is made to hardening of the arteries, this usually refers to atherosclerosis; the terms arteriosclerosis and atherosclerosis are often used interchangeably.
It is the responsibility of the health care provider to help individuals modify or eliminate from their lives risk factors for the development of arteriosclerosis. These include cigarette smoking, obesity, elevated cholesterol levels, and sedentary life style.Mönckeberg's arteriosclerosis see arteriosclerosis.arteriosclerosis obli´terans arteriosclerosis in which proliferation of the intima has caused complete obliteration of the lumen of the artery. Cf. endarteritis obliterans.

ar·te·ri·o·scle·ro·sis

(ar-tēr'ē-ō-skler-ō'sis), Hardening of the arteries; types generally recognized are: atherosclerosis, Mönckeberg arteriosclerosis, and arteriolosclerosis. Synonym(s): arterial sclerosis, arteriosclerotic heart disease, vascular sclerosis [arterio- + G. sklērōsis, hardness]

arteriosclerosis

(är-tîr′ē-ō-sklə-rō′sĭs)n. Any of several chronic diseases, such as atherosclerosis, that are characterized by thickening and loss of elasticity of the walls of the arteries and that lead to impaired blood circulation.

ar·te′ri·o·scle·rot′ic (-rŏt′ĭk) adj.

arteriosclerosis

A group of diseases, more commonly affecting men over age 50, characterised by thickening and hardening of arterial walls due to accumulation of lipids, calcium and fibrosis, as well as loss of elasticity and narrowing of arterial lumina. ASHD’s early effects are in the lower extremities, with subtotal occlusion and decreased exercise tolerance.
Forms
▪ Arteriolosclerosis:
– Benign—associated with hyaline arteriolosclerosis;
– Malignant—associated with myofibroblast hyperplasia, “onion-skinning” of endothelial basement membrane, and deposit of fibrinoid material in vascular wall.
▪ Atherosclerosis—Formed by cholesterol and cholesterol esters, covered by a fibrous plaque which with time becomes calcified, ulcerated and causes thromboembolism in coronary artery disease (strokes, MIs, leg ischaemia, ischaemia of large intestine).
▪ Mönckeberg sclerosis—Idiopathic and often asymptomatic annular calcified bands occurring in the muscular media of medium to small blood vessels of the extremities.

Risk factors
Personal or family history of coronary artery or cerebrovascular disease; diabetes; hypertension; kidney disease involving haemodialysis; smoking; obesity.

arteriosclerosis

ASHD, hardening of the arteries Cardiology ASHD's early effects are in the lower extremities, with subtotal occlusion and decreased ability to withstand exercise without frequent rest periods; atherosclerosis is a generic term for arterial 'hardening'–calcium deposition, sclerosis, and thickening by fibrous tissue with loss of elasticity forms of arteriosclerosis including atherosclerosis–in which there is lipid deposition, Mönckeberg sclerosis, arteriolosclerosis; it is a common disorder usually affecting > age 50 and refers to any of a group of diseases characterized by thickening and hardening of the artery wall and in the narrowing of its lumen Risk factors Personal or family history of coronary artery or cerebrovascular disease, DM, HTN, kidney disease involving hemodialysis, smoking, or obesity. See Atherosclerosis, Hyaline arteriosclerosis.

Arteriosclerosis

Arteriolosclerosis

Benign–associated with hyaline arteriolosclerosis
Malignant–associated with myofibroblast hyperplasia, 'onion-skinning' of endothelial basement membrane and deposit of fibrinoid material in vascular wall

Atherosclerosis

Formed by cholesterol and cholesterol esters, covered by a fibrous plaque which, with time becomes calcified, ulcerated and causes thromboembolism in coronary artery disease–strokes, MIs, leg ischemia-especially in DM, ischemia of large intestine

Mönckeberg sclerosis

Idiopathic and often asymptomatic annular calcified bands occurring in the muscular media of medium to small blood vessels of the extremities that have been fancifully likened to a goose's neck

ar·te·ri·o·scle·ro·sis

(ahr-tēr'ē-ō-skler-ō'sis) Hardening of the arteries; types generally recognized are: atherosclerosis, Mönckeberg arteriosclerosis, and arteriolosclerosis.
Synonym(s): arterial sclerosis. [L. arteria, + G. sklērōsis, hardness]

arteriosclerosis

Hardening of the arteries. The term, once ubiquitous, has become imprecise and has virtually fallen out of use because pure arteriosclerosis is rare. It has been replaced by the term ATHEROSCLEROSIS, which more accurately describes the common degenerative disease of arteries. Pure arteriosclerosis may occur as a result of calcium deposition in the middle coat (media) of arteries, reducing their elasticity.

arteriosclerosis

a pathological condition or any of a group of diseases in which there is an increase in the thickness of the arterial walls, a reduction in elasticity of the vessel, and a constriction of diameter which affects the blood flow; the classic ‘hardening of the arteries’ of the elderly. See ATHEROMA.

Arteriosclerosis

A chronic condition characterized by thickening and hardening of the arteries and the build-up of plaque on the arterial walls. Arteriosclerosis can slow or impair blood circulation.Mentioned in: Aneurysmectomy, Angiography, Atherosclerosis, Dizziness, Gangrene, Hypertension, Hypotension

arteriosclerosis

Thickening and hardening of the walls of arteries which results in an obstruction of the blood flow. It is most frequently the result of hypertension but in the elderly it can develop in the absence of hypertension. In the retina, the branches of the central retinal artery may become straightened at first, later they become lengthened and tortuous, the arteriovenous (A-V) crossings are abnormal. Arteries resemble 'copper wire' as they become infiltrated with lipid deposits and eventually as 'silver wire' as the deposits increase and the whole thickness of the artery appears as a bright white reflex. Some retinal oedema may be present and as the disease progresses there are retinal haemorrhages and small sharp-edged exudates without surrounding oedema. This retinal condition is called arteriosclerotic retinopathy. See atherosclerosis; anterior ischaemic optic neuropathy; hypertensive retinopathy; sphygmomanometer.

arteriosclerosis

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Synonyms for arteriosclerosis

noun sclerosis of the arterial walls

Synonyms

Related Words