单词 | smurf-1 |
释义 | Smurf-1Smurf-1Smad ubiqiutination regulatory factor 1. An E3 ubiquitin ligase that participates in a cascade of ubiquitin transfer reactions, targeting R-Smad1 and R-Smad5 for ubiquitination and proteosomal degradation; it appears to specifically control BMP signalling and reduce intracellular levels of R-Smads independent of BMP ligand stimulation. |
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