triple-negative breast cancer


triple-negative breast cancer

An aggressive form of breast cancer which is negative for oestrogen and progesterone receptors and for HER2. It overlaps with, but is not the same as, basal-like breast cancer. The therapeutic impact of triple negativity is that these tumours do not respond to endocrine activity nor to anti-HER2 agents; despite poor prognosis, some subgroups have a good outcome.