Pribnow box

ho·me·o·box

(hō'mē-ō-boks), A highly conserved DNA sequence of about 180 base pairs near the 3' end of specific homeotic genes; it encodes a DNA-binding domain that allows the homeobox proteins to bind to and regulate gene expression in development. Synonym(s): homeodomain

Pribnow box

a NUCLEOTIDE sequence found in prokaryotic PROMOTERS that is required for initiation of TRANSCRIPTION. It allows the RNA POLYMERASE to position itself correctly at the transcription start site on DNA. The CONSENSUS SEQUENCE is 5′-TATAAT-3′.

Sometimes it is called the -10 sequence, because of its location UPSTREAM of the transcription start. The Pribnow box was named after D Pribnow, who first pointed out such sequences.

Pribnow,

David, 20th century U.S. molecular biologist. Pribnow box - a highly conserved DNA sequence of about 180 base pairs near the 3' end of specific homeotic genes.

单词	pribnow box
释义	DictionarySeehomeobox Pribnow box Pribnow box [′prib‚nō ‚bäks] (cell and molecular biology) In prokaryotes, a highly conserved sequence element located upstream from the transcriptional start site to which binds the sigma subunit of the ribonucleic acid polymerase. Pribnow box ho·me·o·box (hō'mē-ō-boks), A highly conserved DNA sequence of about 180 base pairs near the 3' end of specific homeotic genes; it encodes a DNA-binding domain that allows the homeobox proteins to bind to and regulate gene expression in development. Synonym(s): homeodomain Pribnow box a NUCLEOTIDE sequence found in prokaryotic PROMOTERS that is required for initiation of TRANSCRIPTION. It allows the RNA POLYMERASE to position itself correctly at the transcription start site on DNA. The CONSENSUS SEQUENCE is 5′-TATAAT-3′. Sometimes it is called the -10 sequence, because of its location UPSTREAM of the transcription start. The Pribnow box was named after D Pribnow, who first pointed out such sequences. Pribnow, David, 20th century U.S. molecular biologist. Pribnow box - a highly conserved DNA sequence of about 180 base pairs near the 3' end of specific homeotic genes. LegalSeeboxFinancialSeeBox
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