Biogenic Stimulants

(stimulants of biological origin), in medicine, biologically active substances formed under certain conditions in animal and plant tissues. The theory of biogenic stimulants was first developed by the Soviet ophthalmologist V. P. Filatov. Biogenic stimulants exert a nonspecific stimulating effect on human bodily functions. Their chemical structure and mechanism of action have not been fully ascertained. Preparations containing biogenic stimulants are made from plant (extract from aloe leaves) and animal tissues subjected to various actions (chilling, storage in the dark, and so on), from peat, and from estuarine (FiBS) and silty (peloid) muds, in which the content of biogenic stimulants is determined by such factors as dead microflora and microfauna. Biogenic stimulants are used in the treatment of inflammatory, degenerative, and atrophic disorders. In animal husbandry, preparations containing biogenic stimulants are used for therapeutic purposes (for slow-healing wounds, ulcers, purulentnecrotic processes in the region of the crest in horses, eye diseases, eczema, bone cracks and fractures, endometritis, placental retention, infertility, mastitis, and some other diseases) and to stimulate the growth of young steers, multiple births of farm animals, and productivity. The most widely used stimulants are liquid tissue preparations for injections, dry tissue preparations for internal use and implantation (dry biogenic stimulants from the embryos of farm animals, dry tissue stimulants from the spleen, liver, and adrenal gland), Dorogov’s antiseptic stimulant, pregnant mare’s serum (SZhK), banked animal blood and its water extract (DZK), acidophilic broth culture (ABK), and propione-acidophilic broth culture (PBK).