primary ciliary dyskinesia


dyskinesia

 [dis-ki-ne´zhah] impairment of the power of voluntary movement.primary ciliary dyskinesia any of a group of hereditary syndromes characterized by delayed or absent mucociliary clearance from the airways; often there is also lack of motion of sperm. One variety is Kartagener's syndrome.tardive dyskinesia an iatrogenic disorder produced by long-term administration of antipsychotic agents; it is characterized by oral-lingual-buccal dyskinesias that usually resemble continual chewing motions with intermittent darting movements of the tongue; there may also be choreoathetoid movements of the extremities. The disorder is more common in women than in men and in the elderly than in the young, and incidence is related to drug dosage and duration of treatment. In some patients symptoms disappear within several months after antipsychotic drugs are withdrawn; in others symptoms may persist indefinitely.

primary ciliary dyskinesia

an apparently autosomal recessive disorder in which mucus clearance is sluggish and bronchiectasis is prevalent and intractable. Evidence suggests the defect lies in dynein, a protein in the cilia. Synonym(s): dyskinesia syndrome

pri·ma·ry cil·i·ar·y dys·ki·ne·si·a

(prīmar-ē silē-ar-ē diski-nēzē-ă) Disorder inwhich mucus clearance is sluggish and bronchiectasis is prevalent and intractable.