| 释义 |
thalassaemia
thalassaemia (ˌθæləˈsiːmɪə) or thalassemian (Pathology) a hereditary disease, common in many parts of the world, resulting from defects in the synthesis of the red blood pigment haemoglobin. Also called: Cooley's anaemia [New Latin, from Greek thalassa sea + -aemia, from it being esp prevalent round the eastern Mediterranean Sea]Thesaurus| Noun | 1. | thalassaemia - an inherited form of anemia caused by faulty synthesis of hemoglobinMediterranean anaemia, Mediterranean anemia, thalassemiamonogenic disease, monogenic disorder - an inherited disease controlled by a single pair of geneshypochromic anaemia, hypochromic anemia - anemia characterized by a decrease in the concentration of corpuscular hemoglobinCooley's anaemia, Cooley's anemia, thalassaemia major, thalassemia major - a fatal form of homozygous thalassemia (inherited from both parents) in which there is no hemoglobin; skeletal deformations; heart and spleen and liver enlarged |
TranslationsEncyclopediaSeeThalassemiathalassaemia
thal·as·se·mi·a , thalassanemia (thal'ă-sē'mē-ă, -ă-să-nē'mē-ă) Any of a group of inherited disorders of hemoglobin metabolism in which there is impaired synthesis of one or more of the polypeptide chains of globin; several genetic types exist, and the corresponding clinical picture may vary from barely detectable hematologic abnormality to severe and fatal anemia. People of Mediterranean, extraction are more often affected than others by this type of anemia.
Synonym(s): thalassaemia, thalassanaemia. [G. thalassa, the sea, + haima, blood]thalassaemia One of several hereditary abnormalities of synthesis of the globin chains of HAEMOGLOBIN leading to severe ANAEMIA. The disorder is common in the area surrounding the Mediterranean sea. When the abnormality is HETEROZYGOUS (thalassaemia minor), disability is minimal, but when HOMOZYGOUS (thalassaemia major), anaemia may be severe with breathlessness, jaundice, spleen enlargement and sometimes physical and mental retardation. Treatment is by blood transfusion and bone marrow transplantation. From the Greek words thelazia , the sea, and haima , blood.thal·as·se·mi·a , thalassanemia (thal'ă-sē'mē-ă, -ă-să-nē'mē-ă) Any of a group of inherited disorders of hemoglobin metabolism with impaired synthesis of one or more polypeptide chains of globin; several genetic types exist.
Synonym(s): thalassaemia, thalassanaemia. [G. thalassa, the sea, + haima, blood]thalassaemia
Related to thalassaemia: Thalassaemia minorSynonyms for thalassaemianoun an inherited form of anemia caused by faulty synthesis of hemoglobinSynonyms- Mediterranean anaemia
- Mediterranean anemia
- thalassemia
Related Words- monogenic disease
- monogenic disorder
- hypochromic anaemia
- hypochromic anemia
- Cooley's anaemia
- Cooley's anemia
- thalassaemia major
- thalassemia major
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