thalassemia intermedia


thal·as·se·mi·a in·ter·me·di·a

a clinical variant of thalassemia characterized by an intermediate degree of severity. These patients have severe anemia but usually do not require regular blood transfusions. Intermedia disorders represent a heterogeneous group of genetic disorders and may include cases with homozygous or heterozygous abnormalities in the β-globin chain gene.

thalassemia intermedia

A chronic hemolytic anemia caused by deficient alpha chain synthesis. Synonym: hemoglobin H diseaseSee also: thalassemia