serpiginous choroidopathy

ser·pig·i·nous cho·roi·dop·a·thy

bilateral acquired abnormality of retinal pigment epithelium and choroid in which irregular multiple progressive swelling is followed by atrophic scars in linear patterns. Synonym(s): geographic choroidopathy, helicoid choroidopathy

An asymmetric maculopathy of middle-aged adults
Diagnosis Fluorescein angiography, early, active lesion has central hypofluorescence with a hyperfluorescent rim; choriocapillaris and retinal pigment epithelium are absent or attenuated in healed lesions making the larger choroidal vessels easily visible clinically and on angiography
Visual field testing Scotomata, densest at the centre
Management Corticosteroids are used, but don’t stop disease progression, long-term combination therapy with prednisone, azathioprine, cyclosporine
DiffDx Multifocal choroiditis; panuveitis; central areolar choroidal sclerosis; sarcoidosis; syphilitic choroiditis; patients with acute posterior multifocal placoid pigment epitheliopathy (APMPPE), are younger, may have extraocular findings, lesions rarely emanate from optic nerve, acute lesions rarely border inactive scars; age-related macular degeneration; angioid streaks

单词	serpiginous choroidopathy
释义	serpiginous choroidopathy ser·pig·i·nous cho·roi·dop·a·thy bilateral acquired abnormality of retinal pigment epithelium and choroid in which irregular multiple progressive swelling is followed by atrophic scars in linear patterns. Synonym(s): geographic choroidopathy, helicoid choroidopathy An asymmetric maculopathy of middle-aged adults Diagnosis Fluorescein angiography, early, active lesion has central hypofluorescence with a hyperfluorescent rim; choriocapillaris and retinal pigment epithelium are absent or attenuated in healed lesions making the larger choroidal vessels easily visible clinically and on angiography Visual field testing Scotomata, densest at the centre Management Corticosteroids are used, but don’t stop disease progression, long-term combination therapy with prednisone, azathioprine, cyclosporine DiffDx Multifocal choroiditis; panuveitis; central areolar choroidal sclerosis; sarcoidosis; syphilitic choroiditis; patients with acute posterior multifocal placoid pigment epitheliopathy (APMPPE), are younger, may have extraocular findings, lesions rarely emanate from optic nerve, acute lesions rarely border inactive scars; age-related macular degeneration; angioid streaks
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