| 释义 |
serum albumin
serum albuminn. The main serum protein of the blood in humans and other vertebrates, produced in the liver and active in the maintenance of blood osmotic pressure, and in the transport of fatty acids, steroids, and other compounds, including many drugs.serum albumin n (Biochemistry) a form of albumin that is the most abundant protein constituent of blood plasma. See also albumin se′rum albu′min
n. the principal protein of blood plasma, important in osmotic regulation of the blood and transport of metabolites: used in the treatment of shock. [1875–80] Thesaurus| Noun | 1. | serum albumin - albumin occurring in blood serum; serves to maintain the somatic pressure of the bloodblood serum, serum - an amber, watery fluid, rich in proteins, that separates out when blood coagulatesalbumen, albumin - a simple water-soluble protein found in many animal tissues and liquids |
serum albumin
serum albumin[′sir·əm al′byü·mən] (biochemistry) The principal protein fraction of blood serum and serous fluids. serum albumin
albumin [al-bu´min] 1. any protein that is soluble in water and moderately concentrated salt solutions and is coagulable by heat.2. serum albumin; the most abundant plasma protein, formed principally in the liver and constituting up to two thirds of the 6 to 8 per cent protein concentration in the plasma. (See accompanying table.) Albumin is responsible for much of the colloidal osmotic pressure of the blood, and thus is a very important factor in regulating the exchange of water between the plasma and the interstitial compartment (space between the cells). Because of hydrostatic pressure, water is forced through the walls of the capillaries into the tissue spaces. This flow of water continues until the osmotic pull of protein (albumin) molecules causes it to stop. A drop in the amount of albumin in the plasma leads to an increase in the flow of water from the capillaries into the interstitial compartment. This results in an increase in tissue fluid which, if severe, becomes apparent as edema. Albumin serves also as a transport protein carrying large organic anions, such as fatty acids, bilirubin, and many drugs, and also hormones, such as cortisol and thyroxine, when their specific binding globulins are saturated.
The presence of albumin in the urine (albuminuria) indicates malfunction of the kidney, and may accompany kidney disease or heart failure. A person with severe renal disease may lose as much as 20 to 30 g of plasma proteins in the urine in one day.
A decrease in the serum albumin level may occur with severe disease of the kidney. Other conditions such as liver disease, malnutrition, and extensive burns may result in serious decrease of plasma proteins.albumin-globulin ratio the ratio of albumin to globulin in blood serum, plasma, or urine.albumin human a preparation of human serum albumin, used as an artificial plasma extender and to increase bilirubin binding in hyperbilirubinemia.iodinated I 125 albumin a radiopharmaceutical used in blood and plasma volume, circulation time, and cardiac output determinations, consisting of albumin human labeled with iodine-125.iodinated I 131 albumin a radiopharmaceutical used in blood pool imaging and plasma volume determinations, consisting of albumin human labeled with iodine-131.normal human serum albumin albumin human.serum albumin albumin of the blood.se·rum al·bu·minthe principal protein in plasma, present in blood plasma and in serous fluids. Participates in fatty acid transport and helps regulate the osmotic pressure of blood. It will also bind hormones, bilirubin, and drugs. Synonym(s): blood albumin, plasma albumin, seralbuminserum albuminn. The main serum protein of the blood in humans and other vertebrates, produced in the liver and active in the maintenance of blood osmotic pressure, and in the transport of fatty acids, steroids, and other compounds, including many drugs.ALB A gene on chromosome 4q13.3 that encodes albumin, the soluble, monomeric protein that comprises the protein in the serum. It serves as a carrier protein for steroids, fatty acids and thyroid hormones; binds well to water, Ca2+, Na2+, K+, fatty acids, hormones, bilirubin and certain drugs; and plays a central role in stabilising extracellular fluid volume. It is produced in the liver as preproalbumin and partially cleaved before its release from the rough endoplasmic reticulum.
Molecular pathology
ALB mutations cause familial dysalbuminemic hyperthyroxinaemia.se·rum al·bu·min (sēr'ŭm al-bū'min) The principal protein in plasma, present in blood plasma and in serous fluids. Participates in fatty acid transport and helps regulate the osmotic pressure of blood.
Synonym(s): blood albumin, seralbumin. serum albumin One of the soluble protein fractions of blood serum. Albumin is important in maintaining the OSMOTIC PRESSURE of the blood.FinancialSeeALBserum albumin
Related to serum albumin: serum globulin, Bovine serum albuminWords related to serum albuminnoun albumin occurring in blood serumRelated Words- blood serum
- serum
- albumen
- albumin
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