ryanodine receptor


ryanodine receptor

receptor associated with a calcium conductance channel in the sarcoplasmic or endoplasmic reticulum of cells, which when bound to ryanodine, causes the channel to remain in a subconductive state, allowing slow continuing release of calcium ions from the sarcoplasmic reticulum into the cytoplasm. The channels are normally sensitive to calcium ions and not sensitive to inositol triphosphate.

ry·an·o·dine re·cep·tor

(rī-an'ō-dēn rĕ-sep'tŏr) Receptor associated with a calcium conductance channel in the sarcoplasmic or endoplasmic reticulum of cells, which, when bound to ryanodine, causes the channel to remain in a subconductive state, allowing slow continuing release of calcium ions from the sarcoplasmic reticulum into the cytoplasm. The channels are normally sensitive to calcium ions and not sensitive to inositol triphosphate.

ryanodine receptor

Abbreviation: RyR
The release channel for calcium ions that is found on the membranes of the sarcoplasmic reticulum of skeletal muscles. See also: receptor