ryanodine receptor 2

A membrane calcium-channel receptor encoded by RYR2 on chromosome 1q43, which is found in cardiac muscle sarcoplasmic reticulum and required for excitation-contraction coupling in cardiac muscle.
Function
Responsible for communication between transverse-tubules (T-tubules) and sarcoplasmic reticulum (SR), resulting in cardiac muscle contraction triggered by Ca2+ release from SR following T-tubule depolarization.
Abnormal in
Stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.

单词	ryanodine receptor 2
释义	ryanodine receptor 2 ryanodine receptor 2 A membrane calcium-channel receptor encoded by RYR2 on chromosome 1q43, which is found in cardiac muscle sarcoplasmic reticulum and required for excitation-contraction coupling in cardiac muscle. Function Responsible for communication between transverse-tubules (T-tubules) and sarcoplasmic reticulum (SR), resulting in cardiac muscle contraction triggered by Ca2+ release from SR following T-tubule depolarization. Abnormal in Stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.
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