arthrogryposis multiplex congenita

ar·thro·gry·po·sis mul·'ti·plex con·gen·'i·ta

[MIM*108110] limitation of range of joint motion and contractures present at birth, usually involving multiple joints; a syndrome probably of diverse etiology that may result from changes in spinal cord, muscle, or connective tissue. Several forms exist, autosomal dominant [MIM*108110, 108120, 108130, 108140, 108145, 108200], recessive [MIM*208080, 208081, 208085, 208100, 208150, 208155, 208200], and X-linked [MIM*301830] Synonym(s): amyoplasia congenita

arthrogryposis multiplex congenita

A rare sporadic condition characterised by joint contractures, dislocations, rigid skeletal deformities (e.g., clubfoot or talipes equinovarus), skin atrophy and replacement of limb muscles with fibrous tissue. AMC is not a sui generis disease, but rather a descriptive term that signifies multiple congenital contractures. The aetiologies encompass both neurogenic and primary myopathic diseases, but most cases are not due to neuromuscular disease.

Pathogenesis
Uncertain; a common link may be intrauterine movement during a critical period of limb development.

Management
Arthrodesis.

ar·thro·gry·po·sis mul·ti·plex con·gen·i·ta

(ahr'thrō-gri-pō'sis mŭl'ti-pleks kon-jen'i-tă) Limitation of range of joint motion and contractures present at birth, usually involving multiple joints; a syndrome probably of diverse etiology that may result from changes in spinal cord, muscle, or connective tissue.

单词	arthrogryposis multiplex congenita
释义	DictionarySeeAMCEncyclopediaSeeArthrogryposis arthrogryposis multiplex congenita ar·thro·gry·po·sis mul·'ti·plex con·gen·'i·ta [MIM108110] limitation of range of joint motion and contractures present at birth, usually involving multiple joints; a syndrome probably of diverse etiology that may result from changes in spinal cord, muscle, or connective tissue. Several forms exist, autosomal dominant [MIM108110, 108120, 108130, 108140, 108145, 108200], recessive [MIM208080, 208081, 208085, 208100, 208150, 208155, 208200], and X-linked [MIM301830] Synonym(s): amyoplasia congenita arthrogryposis multiplex congenita A rare sporadic condition characterised by joint contractures, dislocations, rigid skeletal deformities (e.g., clubfoot or talipes equinovarus), skin atrophy and replacement of limb muscles with fibrous tissue. AMC is not a sui generis disease, but rather a descriptive term that signifies multiple congenital contractures. The aetiologies encompass both neurogenic and primary myopathic diseases, but most cases are not due to neuromuscular disease. Pathogenesis Uncertain; a common link may be intrauterine movement during a critical period of limb development. Management Arthrodesis. ar·thro·gry·po·sis mul·ti·plex con·gen·i·ta (ahr'thrō-gri-pō'sis mŭl'ti-pleks kon-jen'i-tă) Limitation of range of joint motion and contractures present at birth, usually involving multiple joints; a syndrome probably of diverse etiology that may result from changes in spinal cord, muscle, or connective tissue. AcronymsSeeair material command
随便看	replacement investment replacement joint replacement joint lancashire structure plan replacement lens insurance replacement level fertility replacement level players association replacement level yankees weblog replacement memory replacement name replacement of knee replacement of legacy electronics replacement of obsolete items replacement operations automated management system replacement parts replacement parts r us replacement post replacement property replacement regulating detachment replacement reserve replacements replacement series replacement service system replacement solution replacement steam generators replacement stream input