| 释义 |
perforinenUK
per·fo·rin P0189350 (pûr′fər-ĭn)n. A protein released by natural killer cells and cytotoxic T lymphocytes that causes lysis of target cells by forming pores in their membranes.
[perfor(ate) + -in.]
perforinenUK
perforin[′pər·fər·ən] (immunology) An enzyme that is secreted by natural killer cells and cytotoxic T cells and destroys foreign cells by puncturing their membranes, causing leakage of the cell contents. Also known as cytolysin; pore-forming protein. perforinenUK
per·for·in (per'fōr-in), A protein found in the cytoplasmic granules of both T-cytotoxic lymphocytes and natural killer cells. This protein is implicated in target cell lysis by the above cells. [L. per-foro, to bore, pierce, + -in] perforin (pûr′fər-ĭn)n. A protein released by killer cells and natural killer cells that causes lysis of target cells by forming pores in their membranes.per·for·in (pĕr'fŏ-rin) A protein found in the cytoplasmic granules of both T-cytotoxic lymphocytes and natural killer cells, implicated in target cell lysis. [L. per-foro, to bore, pierce, + -in]perforin A molecule produced by cytotoxic T cells and natural killer cells which forms a pore in the membrane of the attacked cell resulting in LYSIS and cell death. A similar process can be brought about by COMPLEMENT.perforin see KILLER T-CELL. |