S100


S100

An acidic, calcium-binding protein characterized by its partial solubility in saturated ammonium sulfate; stains for S100 are used in the differential diagnosis of melanomas, which are commonly positive for S100.

S100A1

A gene on chromosome 1q21 that encodes a member of the S100 family of proteins, which have 2 EF-hand calcium-binding motifs. S100 proteins are localised in the cytoplasm and/or nucleus of a wide range of cells, and involved in regulating cell cycle progression and differentiation and other intracellular activities.

S100

An acidic, calcium-binding protein characterized by its partial solubility in saturated ammonium sulfate; stains for S100 are used in the differential diagnosis of melanomas, which are commonly positive for S100.