| Acronym | Definition |
|---|
| S2S➣Server-to-Server (computer protocol) |
| S2S➣System-to-System (gaming protocol) |
| S2S➣Site to Site |
| S2S➣Side to Side |
| S2S➣Server to Server |
| S2S➣System to System |
| S2S➣Ship to Shore |
| S2S➣Site-to-Site |
| S2S➣Surfaced Two Sides (lumber) |
| S2S➣Student 2 Student (Washington) |
| S2S➣Source to Settle |
| S2S➣Service-to-Service (software) |
| S2S➣So to Speak |
| S2S➣Swim to Survive (Canada) |