| 单词 | amoxapine |
| 释义 | amoxapineamoxapine[ah-mok´sah-pēn]amoxapineA tricyclic antidepressant of the dibenzoxazepine class.Adverse effects Tardive dyskinesia, sedation, postural hypotension, cholinergic effects (e.g., dry mouth, blurred vision, constipation, urinary retention, weight gain), neuroleptic malignant syndrome, cardiovascular effects (EKG, slow AV conduction); withdrawal symptoms accompany abrupt withdrawal. Toxic range > 500 ng/mL. T1/2 30 hours as metabolite (8-hydroxyamoxipine). Method HPLC. amoxapineNeuropharmacology A tricyclic antidepressant Adverse effects Tardive dyskinesia, sedation, postural hypotension, cholinergic effects—eg dry mouth, blurred vision, constipation, urinary retention, weight gain, neuroleptic malignant syndrome, cardiovascular effects—EKG, slow AV conduction; withdrawal symptoms accompany abrupt withdrawalamoxapineA tricyclic antidepressant drug similar to IMIPRAMINE. Overdosage may cause acute kidney failure, convulsions and coma. A brand name is Asendis. |
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