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Reed-Sternberg cell
Reed-Stern·berg cell R0110850 (rēd′stûrn′bûrg′)n. A large, abnormal, binucleated or multinucleated B cell that is characteristic of Hodgkin lymphoma.
[After Dorothy M. Reed (1874-1964), American pathologist, and Carl Sternberg (1872-1935), Austrian pathologist.]
Reed-Sternberg cell
Reed-Sternberg cell[′rēd ′stərn‚bərg ‚sel] (pathology) An anaplastic reticuloendothelial cell constituting the characteristic microscopic feature of Hodgkin's disease. Reed-Sternberg cell
Reed-Stern·berg cell (rēd shtĕrn'bĕrg), large transformed lymphocytes, probably B cell in origin, generally regarded as pathognomonic of Hodgkin disease; a typical cell has a pale-staining acidophilic cytoplasm and one or two large nuclei showing marginal clumping of chromatin and unusually conspicuous deeply acidophilic nucleoli; binucleate Reed-Sternberg cell frequently shows a mirror-image form (mirror-image cell). Synonym(s): Reed cell, Sternberg cell, Sternberg-Reed cellReed-Sternberg cell (rēd′stûrn′bûrg′)n. A large, abnormal, binucleated or multinucleated B cell that is characteristic of Hodgkin lymphoma.Reed-Stern·berg cell (rēd-stĕrn'bĕrg sel) Large transformed lymphocytes, probably B cell in origin, generally regarded as pathognomonic of Hodgkin lymphoma; a typical cell has a pale-staining acidophilic cytoplasm and one or two large nuclei showing marginal clumping of chromatin and unusually conspicuous deeply acidophilic nucleoli; binucleate Reed-Sternberg cells frequently show a mirror-image form (mirror-image cell).  REED-STERNBERG CELL: Reed-Sternberg cell in Hodgkin LymphomaReed-Sternberg cell (rēd′stĕrn′bĕrg″) [Dorothy Reed, U.S. pathologist, 1874–1964; Karl Sternberg, Aust. pathologist, 1872–1935] A giant, malignant, multinucleated B lymphocyte, the presence of which is the pathologic hallmark of Hodgkin's disease. See: illustrationReed-Sternberg cell A giant cell with paired, mirror-image nuclei that is a diagnostic feature of HODGKIN'S LYMPHOMA and distinguishes it from non-Hodgkin's lymphoma. (Dorothy M. Reed, 1874–1964, American pathologist; and Karl von Sternberg, 1872–1935, Austrian pathologist).AcronymsSeeRSC |