| 单词 | sf3b4 |
| 释义 | SF3B4SF3B4A gene on chromosome 1q21.2 that encodes subunit 4 of the splicing factor SF3B, which is required for “A” complex assembly by the stable binding of U2 snRNP to the branchpoint sequence in pre-mRNA. It may anchor U2 snRNP to pre-mRNA and be involved in the assembly of the “E” complex. SF3B4 is also found in complexes B and C and belongs to the U12-dependent spliceosome, which is involved in splicing the nuclear pre-mRNA intron. |
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