superwarfarin

superwarfarin

Toxicology A warfarin–eg, brodifacoum, bromadiolone, difenacou, which is up to 100-fold more toxic, and has a T1/2 60 times longer than warfarin; ingestion causes severe and prolonged coagulopathy

superwarfarin

(soo″pĕr-wor′fă-rĭn) Any of a group of anticoagulant drugs derived from warfarin, used principally for their toxic effect on vermin. Agents in this class have a long half life (weeks to months) compared with warfarin (half life about 1.5 days). They inhibit the synthesis of vitamin K-dependent clotting factors. The principal toxic effect is bleeding. Brodifacoum is a commonly used superwarfarin in the U.S.