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pernicious
per·ni·cious P0202000 (pər-nĭsh′əs)adj.1. Tending to cause death or serious injury; deadly: a pernicious virus.2. Causing great harm; destructive: pernicious rumors.
[Middle English, from Old French pernicios, from Latin perniciōsus, from perniciēs, destruction : per-, per- + nex, nec-, violent death; see nek- in Indo-European roots.]
per·ni′cious·ly adv.per·ni′cious·ness n.pernicious (pəˈnɪʃəs) adj1. wicked or malicious: pernicious lies. 2. causing grave harm; deadly[C16: from Latin perniciōsus, from perniciēs ruin, from per- (intensive) + nex death] perˈniciously adv perˈniciousness nper•ni•cious (pərˈnɪʃ əs)
adj. 1. causing insidious harm or ruin; ruinous: a pernicious lie. 2. Obs. evil; wicked. [1515–25; < Latin perniciōsus ruinous =pernici(ēs) ruin (per- per- + -nici-, comb. form of nex death, murder (s. nec-) + -iēs n. suffix) + -ōsus -ous] per•ni′cious•ly, adv. per•ni′cious•ness, n. Thesaurus| Adj. | 1. |  pernicious - exceedingly harmful baneful, pestilent, deadlynoxious - injurious to physical or mental health; "noxious chemical wastes"; "noxious ideas" | | 2. | pernicious - working or spreading in a hidden and usually injurious way; "glaucoma is an insidious disease"; "a subtle poison"insidious, subtleharmful - causing or capable of causing harm; "too much sun is harmful to the skin"; "harmful effects of smoking" |
perniciousadjective (Formal) wicked, bad, damaging, dangerous, evil, offensive, fatal, deadly, destructive, harmful, poisonous, malicious, malign, malignant, detrimental, hurtful, malevolent, noxious, venomous, ruinous, baleful, deleterious, injurious, noisome, baneful (archaic), pestilent, maleficent the pernicious effects of alcoholismperniciousadjective1. Extremely destructive or harmful:baneful, deadly, malignant, noxious, pestilent, pestilential, virulent.2. Having the capability or effect of damaging irreparably:destructive, ruinous.Translationsdélétèremalsainnocifnuisiblepernicieuxdannosoperniciosodestructiefdodelijkschadelijk
EncyclopediaSeepernicious anemiapernicious
pernicious [per-nish´us] tending to a fatal outcome.pernicious anemia a type of anemia" >megaloblastic anemia seen most often in older adults, caused by lack of factor" >intrinsic factor, which normally is produced by the stomach mucosa. The deficiency results in inadequate and abnormal formation of erythrocytes, leukocytes, and platelets, with failure to absorb vitamin B12. Some patients show only mild symptoms and are not particularly aware of the illness; in others it becomes very serious and if untreated can lead to permanent neurologic impairment and even death. It may be caused by deficient vitamin B12 intake, impaired absorption due to intrinsic factor deficiency or intrinsic intestinal disease or increased requirements and impaired utilization.Symptoms. A pale, colorless, or lemon-yellow complexion is typical. jaundice also occurs, with soreness and reddening of the tongue, difficulty in swallowing, and digestive disturbances such as diarrhea. Other symptoms may include fatigability, heart palpitation, and dyspnea. Changes in the nerves and spinal cord may produce numbness and tingling in the fingers and toes, and the gait may become unsteady; involvement of the nerves can be avoided if the condition is detected and treated in the early stages. Laboratory tests reveal abnormalities in the erythrocytes in the blood and in the bone marrow. Gastric analysis shows an absence of hydrochloric acid and perhaps even an absence of gastric juice.Treatment. Pernicious anemia is successfully treated by regular injections of vitamin B12, given several times a week at first and monthly after the condition has been brought under control. This treatment must be lifelong to prevent relapse. The injections do not cure the disease but arrest it by providing the body directly with the necessary vitamin that it fails to absorb from the digestive tract. Special diets, liver extract, and other medications taken by mouth usually are not required since the basic defect is not dietary deficiency but improper use of food ingested. The etiology of pernicious anemia is unknown although there appears to be an autoimmune component, as anti–intrinsic factor antibodies are often found. For patient care, see also anemia.per·ni·cious (per-nish'ŭs), Destructive; harmful; denoting a disease of severe character and usually fatal without appropriate treatment. [L. perniciosus, destructive, fr. pernicies, destruction] pernicious adjective Bad/not real goodper·ni·ci·ous (pĕr-nish'ŭs) Destructive; harmful; denoting a disease of severe character and usually fatal without appropriate treatment. [L. perniciosus, destructive, fr. pernicies, destruction]per·ni·ci·ous (pĕr-nish'ŭs) Destructive; denoting a disease of severe character and usually fatal without appropriate treatment. [L. perniciosus, destructive, fr. pernicies, destruction]pernicious
Related to pernicious: pernicious anemia, wangleSynonyms for perniciousadj wickedSynonyms- wicked
- bad
- damaging
- dangerous
- evil
- offensive
- fatal
- deadly
- destructive
- harmful
- poisonous
- malicious
- malign
- malignant
- detrimental
- hurtful
- malevolent
- noxious
- venomous
- ruinous
- baleful
- deleterious
- injurious
- noisome
- baneful
- pestilent
- maleficent
Synonyms for perniciousadj extremely destructive or harmfulSynonyms- baneful
- deadly
- malignant
- noxious
- pestilent
- pestilential
- virulent
adj having the capability or effect of damaging irreparablySynonymsSynonyms for perniciousadj exceedingly harmfulSynonymsRelated Wordsadj working or spreading in a hidden and usually injurious waySynonymsRelated Words |